Assay Detail
Binding
CHEMBL4686970
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Inhibition of human Norovirus RNA-dependent RNA polymerase assessed as decrease in GTP incorporation incubated for 10 mins by scintillation counting method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Norovirus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Anti-norovirus activity of C7-modified 4-amino-pyrrolo[2,1-f][1,2,4]triazine C-nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.38 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL265502 | SURAMIN | 3.0 | 1 | 7.60 |
| CHEMBL1206126 | — | — | 1 | 7.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL265502 | SURAMIN | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL1206126 | — | IC50 | = | 71.0 | nM | 7.15 |