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Assay Detail

CHEMBL4687283

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of PAF-induced platelet aggregation in rabbit platelet suspension preincubated for 10 mins followed by PAF stimulation by turbidimetric method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Oryctolagus cuniculus
Cell Type Platelet
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis.
Foster H,Wilson C,Philippou H,Foster R
J Med Chem (2020) 63 : 12213 -12242
PubMed 32463237 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.86 4.86

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL549359 GLAUCOCALYXIN A 1 4.86

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL549359 GLAUCOCALYXIN A IC50 = 13700.0 nM 4.86