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Assay Detail

CHEMBL4687296

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of collagen-induced human platelet aggregation preincubated for 20 mins followed by collagen stimulation and measured for 10 mins by aggregometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Platelet
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis.
Foster H,Wilson C,Philippou H,Foster R
J Med Chem (2020) 63 : 12213 -12242
PubMed 32463237 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.55 5.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL228043 1 5.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL228043 IC50 = 2800.0 nM 5.55