Assay Detail
Binding
CHEMBL4687516
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Inhibition of Influenza A virus (A/Anhui/1/2005 (H5N1-H274Y)) Neuraminidase using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Influenza A virus (A/Anhui/1/2005(H5N1)) |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of a non-zwitterionic oseltamivir analogue as a potent influenza a neuraminidase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.46 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4797391 | — | — | 1 | 5.70 |
| CHEMBL674 | OSELTAMIVIR CARBOXYLATE | -1.0 | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4797391 | — | IC50 | = | 2005.0 | nM | 5.70 |
| CHEMBL674 | OSELTAMIVIR CARBOXYLATE | IC50 | = | 6095.0 | nM | 5.21 |