Assay Detail
Binding
CHEMBL4687583
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Enhancement of RNA interference pathway in HEK293 cells expressing 293-EGFP and shRNA assessed as increase in siRNA-mediated gene knockdown incubated for 24 hrs by inverted fluorescence microscopy
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.52 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL826 | ENOXACIN | 4.0 | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL826 | ENOXACIN | EC50 | = | 30000.0 | nM | 4.52 |