Assay Detail
Binding
CHEMBL4687635
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Inhibition of rat NTPDase3 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | CHO |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Targeting Metabolism of Extracellular Nucleotides via Inhibition of Ectonucleotidases CD73 and CD39.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.47 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4744335 | — | — | 1 | 5.96 |
| CHEMBL597197 | — | — | 1 | 5.65 |
| CHEMBL271673 | — | — | 1 | 4.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4744335 | — | Ki | = | 1100.0 | nM | 5.96 |
| CHEMBL597197 | — | Ki | = | 2220.0 | nM | 5.65 |
| CHEMBL271673 | — | Ki | = | 16400.0 | nM | 4.79 |