Assay Detail
Binding
CHEMBL4687750
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]Bolton-Hunter CCK8 from human Cholecystokinin B receptor expressed in CHO-K1 cells by competitive radioligand binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Gastrin/cholecystokinin type B receptor (CHEMBL298) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Opportunities for Tapping into Three-Dimensional Chemical Space through a Quaternary Carbon.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.90 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL432015 | — | — | 1 | 6.55 |
| CHEMBL317181 | — | — | 1 | 6.08 |
| CHEMBL88239 | — | — | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL432015 | — | IC50 | = | 281.84 | nM | 6.55 |
| CHEMBL317181 | — | IC50 | = | 831.76 | nM | 6.08 |
| CHEMBL88239 | — | IC50 | = | 8317.64 | nM | 5.08 |