Assay Detail
Binding
CHEMBL4687763
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at TLR2 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 9.46 | 9.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4756806 | — | — | 1 | 9.55 |
| CHEMBL4759425 | — | — | 1 | 9.52 |
| CHEMBL4791879 | — | — | 1 | 9.42 |
| CHEMBL4780449 | — | — | 1 | 9.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4756806 | — | EC50 | = | 0.28 | nM | 9.55 |
| CHEMBL4759425 | — | EC50 | = | 0.3 | nM | 9.52 |
| CHEMBL4791879 | — | EC50 | = | 0.38 | nM | 9.42 |
| CHEMBL4780449 | — | EC50 | = | 0.47 | nM | 9.33 |