Assay Detail

CHEMBL4687799

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Binding

Displacement of [3H]-MK801 from NMDA receptor in ICR Harlan mouse brain homogenate incubated for 45 mins by liquid scintillation spectrometry

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Mus musculus
Tissue	Brain
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Repurposing of Drugs-The Ketamine Story.

Das J
J Med Chem (2020) 63 : 13514 -13525
PubMed 32915563 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	6.75	6.75

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL742	KETAMINE	4.0	1	6.75

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL742	KETAMINE	Ki	=	180.0	nM	6.75