Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4689467

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) assessed as using DP-G1cNAc as substrate preincubated for 15 mins by HPLC method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Staphylococcus aureus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
Scherzi T,D'Ambrosio EA,Daher SS,Grimes CL,Dunman PM,Andrade RB
Bioorg Med Chem (2021) 32 : 115995 -115995
PubMed 33477021 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.63 4.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4128170 1 4.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4128170 Ki = 23600.0 nM 4.63