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Assay Detail

CHEMBL4689581

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [125I]-AB-MECA from human A3AR expressed in CHO cells measured after 60 mins by liquid scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Biological Evaluation of 5'-(N-Ethylcarboxamido)adenosine Analogues as Grp94-Selective Inhibitors.
Tosh DK,Brackett CM,Jung YH,Gao ZG,Banerjee M,Blagg BSJ,Jacobson KA
ACS Med Chem Lett (2021) 12 : 373 -379
PubMed 33738064 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.41 8.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL193692 1 8.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL193692 Ki = 3.9 nM 8.41