Assay Detail
Functional
CHEMBL4699739
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Application of triazoles as bioisosteres and linkers in the development of microtubule targeting agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.49 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4743390 | — | — | 1 | 7.96 |
| CHEMBL4761168 | — | — | 1 | 5.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4743390 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL4761168 | — | IC50 | = | 9710.0 | nM | 5.01 |