Assay Detail
Functional
CHEMBL4700064
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Growth inhibition of human Jeko-1 cells incubated for 72 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | JeKo-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Understanding the mechanism of action of pyrrolo[3,2-b]quinoxaline-derivatives as kinase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.23 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4784484 | — | — | 1 | 6.60 |
| CHEMBL4792853 | — | — | 1 | 6.22 |
| CHEMBL5416410 | DASATINIB | 4.0 | 1 | 5.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4784484 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL4792853 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL5416410 | DASATINIB | IC50 | = | 1325.0 | nM | 5.88 |