Assay Detail
Binding
CHEMBL4700265
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Covalent inhibition of Trypanosoma cruzi cruzipain using Z-Phe-Arg-7-amidomethylcoumarin as substrate measured after 30 mins by fluorometric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trypanosoma cruzi |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
On the intrinsic reactivity of highly potent trypanocidal cruzain inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.75 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4217414 | — | — | 1 | 8.80 |
| CHEMBL604281 | — | — | 1 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4217414 | — | Ki | = | 1.585 | nM | 8.80 |
| CHEMBL604281 | — | Ki | = | 1.995 | nM | 8.70 |