Assay Detail

CHEMBL4700288

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Functional

Cytotoxicity against human MDA-MB-231 cells in dark

ChEMBL ↗

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Target

MDA-MB-231 (CHEMBL400) ↗

Open DB target context

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MDA-MB-231 (CHEMBL400) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target MDA-MB-231

CHEMBL400

Anchored from Assay target.

Protein identity MDA-MB-231

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	MDA-MB-231
Confidence	1 — Organism
Curated By	Autocuration

Target

MDA-MB-231 (CHEMBL400) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Photocontrolled activation of small molecule cancer therapeutics

Dcona, M. Michael, Mitra, Koushambi, Hartman, Matthew C. T.
RSC Med Chem (2020) 11 : 982 -1002
PubMed 33479692 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	4.42	4.42

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4165093	—	—	1	4.42

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4165093	—	EC50	=	38000.0	nM	4.42