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Assay Detail

CHEMBL4700369

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against human Cytomegalovirus UL56 infected in human MRC5 cells assessed as reduction in infection rate incubated for 6 days by Hoechst 33342 staining based microscopic analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human betaherpesvirus 5
Cell Type MRC5
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

A3- and A2B-fluorocorroles: synthesis, X-ray characterization and antiviral activity evaluation against human cytomegalovirus infection
Kappler-Gratias, Sandrine, Bucher, Leo, Desbois, Nicolas, Rousselin, Yoann, Bystricky, Kerstin, Gros, Claude P., Gallardo, Franck
RSC Med Chem (2020) 11 : 783 -801
PubMed 33479675 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.40 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1241951 LETERMOVIR 4.0 1 8.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1241951 LETERMOVIR IC50 = 4.0 nM 8.40