Assay Detail
Functional
CHEMBL4700409
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human SCC-15 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SCC-15 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Continuous flow synthesis of lipophilic cations derived from benzoic acid as new cytotoxic chemical entities in human head and neck carcinoma cell lines
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.53 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4788330 | — | — | 1 | 5.57 |
| CHEMBL4780051 | — | — | 1 | 5.54 |
| CHEMBL3234100 | — | — | 1 | 5.52 |
| CHEMBL4796140 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4788330 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL4780051 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL3234100 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL4796140 | — | IC50 | = | 3200.0 | nM | 5.50 |