Assay Detail
ADMET
CHEMBL4700410
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Cytotoxicity against human OKF-6/TERT cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | OKF6 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Continuous flow synthesis of lipophilic cations derived from benzoic acid as new cytotoxic chemical entities in human head and neck carcinoma cell lines
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.95 | 5.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4780051 | — | — | 1 | 5.12 |
| CHEMBL4796140 | — | — | 1 | 4.90 |
| CHEMBL3234100 | — | — | 1 | 4.88 |
| CHEMBL4788330 | — | — | 1 | 4.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4780051 | — | IC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL4796140 | — | IC50 | = | 12700.0 | nM | 4.90 |
| CHEMBL3234100 | — | IC50 | = | 13100.0 | nM | 4.88 |
| CHEMBL4788330 | — | IC50 | = | 13200.0 | nM | 4.88 |