Assay Detail
Functional
CHEMBL4701441
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Antiproliferative activity against human MOLT4 cells incubated for 72 hrs by cell titer glo assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MOLT-4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent Developments in the Biology and Medicinal Chemistry of CDK9 Inhibitors: An Update.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.37 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4786559 | — | — | 1 | 8.05 |
| CHEMBL4587232 | — | — | 1 | 7.30 |
| CHEMBL296468 | BMS-387032 | 1.0 | 1 | 6.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4786559 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL4587232 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL296468 | BMS-387032 | IC50 | = | 173.0 | nM | 6.76 |