Assay Detail
Binding
CHEMBL4701856
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-Diprenorphine from recombinant human delta opioid receptor expressed in CHO cell membrane incubated for 60 mins by liquid scintillation counting method
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure-Activity Relationship Studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 12 | 7.11 | 8.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3408737 | — | — | 1 | 8.82 |
| CHEMBL4761165 | — | — | 1 | 7.33 |
| CHEMBL4749016 | — | — | 1 | 7.31 |
| CHEMBL4789659 | — | — | 1 | 7.25 |
| CHEMBL4745899 | — | — | 1 | 7.21 |
| CHEMBL4776986 | — | — | 1 | 7.00 |
| CHEMBL4742666 | — | — | 1 | 6.98 |
| CHEMBL4798887 | — | — | 1 | 6.80 |
| CHEMBL4747286 | — | — | 1 | 6.70 |
| CHEMBL4750783 | — | — | 1 | 6.68 |
| CHEMBL4744531 | — | — | 1 | 6.67 |
| CHEMBL4758754 | — | — | 1 | 6.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3408737 | — | Ki | = | 1.51 | nM | 8.82 |
| CHEMBL4761165 | — | Ki | = | 46.4 | nM | 7.33 |
| CHEMBL4749016 | — | Ki | = | 48.6 | nM | 7.31 |
| CHEMBL4789659 | — | Ki | = | 56.4 | nM | 7.25 |
| CHEMBL4745899 | — | Ki | = | 60.9 | nM | 7.21 |
| CHEMBL4776986 | — | Ki | = | 101.0 | nM | 7.00 |
| CHEMBL4742666 | — | Ki | = | 105.0 | nM | 6.98 |
| CHEMBL4798887 | — | Ki | = | 159.0 | nM | 6.80 |
| CHEMBL4747286 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL4750783 | — | Ki | = | 209.0 | nM | 6.68 |
| CHEMBL4744531 | — | Ki | = | 213.0 | nM | 6.67 |
| CHEMBL4758754 | — | Ki | = | 276.0 | nM | 6.56 |