Assay Detail
Functional
CHEMBL4702997
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Inhibition of anti-human CD3/CD28/mAbs-stimulated human T-cell proliferation after 72 hrs by CFSE staining based flow cytometric analysis
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T cell |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Compounds from Toddalia asiatica: Immunosuppressant Activity and Absolute Configurations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 2 | - | - |
| IC50 | 2 | 5.79 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8443 | NITIDINE CHLORIDE | — | 2 | 6.40 |
| CHEMBL487807 | — | — | 2 | 5.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8443 | NITIDINE CHLORIDE | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL487807 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL8443 | NITIDINE CHLORIDE | Inhibition | - | % | - | |
| CHEMBL487807 | — | Inhibition | - | % | - |