Assay Detail
Functional
CHEMBL4703485
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Enterovirus D68 US/KY/14-18953 infected in RD cells assessed as reduction in virus yield by visual inspection method
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | enterovirus D68 |
| Cell Type | RD |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure activity relationship of novel antiviral nucleosides against Enterovirus A71.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.00 | 7.50 |
| EC90 | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL283403 | ENVIROXIME | 2.0 | 1 | 7.50 |
| CHEMBL3905850 | — | — | 1 | 4.50 |
| CHEMBL2012686 | — | — | 1 | - |
| CHEMBL4751718 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL283403 | ENVIROXIME | EC50 | = | 32.0 | nM | 7.50 |
| CHEMBL3905850 | — | EC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL2012686 | — | EC90 | = | 15.0 | uM | - |
| CHEMBL4751718 | — | EC90 | = | 7.7 | uM | - |