Assay Detail
Functional
CHEMBL4703493
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Antiviral activity against Poliovirus 1 Mahoney infected in monkey Vero 76 cells assessed as reduction in virus-induced cytopathic effect by neutral red uptake assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Poliovirus 1 |
| Cell Type | Vero 76 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure activity relationship of novel antiviral nucleosides against Enterovirus A71.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.57 | 4.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3905850 | — | — | 1 | 4.57 |
| CHEMBL283403 | ENVIROXIME | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3905850 | — | EC50 | = | 27000.0 | nM | 4.57 |
| CHEMBL283403 | ENVIROXIME | EC50 | < | 10.0 | nM | - |