Assay Detail
Functional
CHEMBL4704204
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Antileishmanial activity against promastigote stage of Leishmania infantum MHOM/PT/88/IMT151 assessed as reduction in parasite viability by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania infantum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Evaluation of the Pharmacophoric Role of the O-O Bond in Synthetic Antileishmanial Compounds: Comparison between 1,2-Dioxanes and Tetrahydropyrans.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.25 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4593142 | — | — | 1 | 5.46 |
| CHEMBL190579 | — | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4593142 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL190579 | — | IC50 | = | 9400.0 | nM | 5.03 |