Assay Detail
Binding
CHEMBL4704735
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Dengue virus 2'-O methyltransferase incubated for 15 mins followed by [methyl-3-H]-AdoMet addition and measured after 30 mins by microbeta counter method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Dengue virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.39 | 7.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1214186 | SINEFUNGIN | 2.0 | 1 | 7.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1214186 | SINEFUNGIN | IC50 | = | 41.0 | nM | 7.39 |