Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4705958

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of human OCILY3 cells grown in soft agar
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type OCI-Ly3
Confidence 1 — Organism
Curated By Autocuration

Target

OCI-Ly3 (CHEMBL4523565)
Type CELL-LINE
Organism Homo sapiens

Publication

Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood.
Quancard J,Simic O,Pissot Soldermann C,Aichholz R,Blatter M,Renatus M,Erbel P,Melkko S,Endres R,Sorge M,Kieffer L,Wagner T,Beltz K,Mcsheehy P,Wartmann M,Régnier CH,Calzascia T,Radimerski T,Bigaud M,Weiss A,Bornancin F,Schlapbach A
J Med Chem (2020) 63 : 14594 -14608
PubMed 33216547 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.62 6.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4748253 1 6.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4748253 IC50 = 240.0 nM 6.62