Assay Detail
Functional
CHEMBL4706444
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Induction of adipogenesis in human BMMSC cotreated with IDX
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | BMMSC |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery and Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.43 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL595 | PIOGLITAZONE | 4.0 | 1 | 6.47 |
| CHEMBL1254751 | — | — | 1 | 5.04 |
| CHEMBL4758410 | — | — | 1 | 4.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL595 | PIOGLITAZONE | EC50 | = | 340.0 | nM | 6.47 |
| CHEMBL1254751 | — | EC50 | = | 9200.0 | nM | 5.04 |
| CHEMBL4758410 | — | EC50 | = | 16140.0 | nM | 4.79 |