Assay Detail
Functional
CHEMBL4708037
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MM.1S cells measured after 72 hrs by MTS assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MM1.S |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.61 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4777582 | — | — | 1 | 5.80 |
| CHEMBL4745360 | — | — | 1 | 5.68 |
| CHEMBL4742685 | — | — | 1 | 5.66 |
| CHEMBL4754311 | — | — | 1 | 5.51 |
| CHEMBL4755837 | — | — | 1 | 5.40 |
| CHEMBL4778505 | — | — | 1 | - |
| CHEMBL115581 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4777582 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL4745360 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL4742685 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL4754311 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL4755837 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL4778505 | — | IC50 | - | — | - | |
| CHEMBL115581 | — | IC50 | - | — | - |