Assay Detail
ADMET
CHEMBL4708038
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Cytotoxicity against human FF2441 cells measured after 72 hrs by MTS assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | FF2441 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.96 | 5.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4777582 | — | — | 1 | 5.27 |
| CHEMBL4745360 | — | — | 1 | 5.01 |
| CHEMBL4754311 | — | — | 1 | 5.00 |
| CHEMBL4755837 | — | — | 1 | 4.86 |
| CHEMBL4742685 | — | — | 1 | 4.68 |
| CHEMBL4778505 | — | — | 1 | - |
| CHEMBL115581 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4777582 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL4745360 | — | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL4754311 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL4755837 | — | IC50 | = | 13900.0 | nM | 4.86 |
| CHEMBL4742685 | — | IC50 | = | 20700.0 | nM | 4.68 |
| CHEMBL4778505 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL115581 | — | IC50 | > | 100000.0 | nM | - |