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Assay Detail

CHEMBL4708146

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human PA-1 cells assessed as inhibition of cell growth measured after 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type PA-1
Confidence 1 — Organism
Curated By Autocuration

Target

PA-1 (CHEMBL614949)
Type CELL-LINE
Organism Homo sapiens

Publication

Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents.
Kumar JS,Thirupataiah B,Medishetti R,Ray A,Bele SD,Hossain KA,Reddy GS,Edwin RK,Joseph A,Kumar N,Shenoy GG,Rao CM,Pal M
Eur J Med Chem (2020) 201 : 112335 -112335
PubMed 32599323 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.12 9.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4759850 1 9.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4759850 IC50 = 0.76 nM 9.12