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Assay Detail

CHEMBL4708223

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Functional
Cytotoxicity against human MV4-11 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MV4-11
Confidence 1 — Organism
Curated By Autocuration

Target

MV4-11 (CHEMBL613835)
Type CELL-LINE
Organism Homo sapiens

Publication

PTG-0861: A novel HDAC6-selective inhibitor as a therapeutic strategy in acute myeloid leukaemia.
Gawel JM,Shouksmith AE,Raouf YS,Nawar N,Toutah K,Bukhari S,Manaswiyoungkul P,Olaoye OO,Israelian J,Radu TB,Cabral AD,Sina D,Sedighi A,de Araujo ED,Gunning PT
Eur J Med Chem (2020) 201 : 112411 -112411
PubMed 32615502 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.24 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4452620 1 6.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4452620 IC50 = 576.0 nM 6.24