Assay Detail
Binding
CHEMBL4710587
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to wild type TTR (unknown origin) assessed as Kd1 by isothermal titration calorimetry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Transthyretin Amyloidogenesis Inhibitors: From Discovery to Current Developments.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 8.52 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2103837 | TAFAMIDIS | 4.0 | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2103837 | TAFAMIDIS | Kd | = | 3.0 | nM | 8.52 |