Assay Detail
Functional
CHEMBL4711685
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Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1 incubated for 48 hrs by parasite lactate dehydrogenase assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydroxypyridinone-Based Iron Chelators with Broad-Ranging Biological Activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.63 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2407845 | — | — | 1 | 7.05 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 6.55 |
| CHEMBL3311433 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2407845 | — | IC50 | = | 89.0 | nM | 7.05 |
| CHEMBL76 | CHLOROQUINE | IC50 | = | 279.0 | nM | 6.55 |
| CHEMBL3311433 | — | IC50 | = | 505.0 | nM | 6.30 |