Assay Detail
Functional
CHEMBL4712366
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Antiproliferative activity against human HeLa cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.75 | 7.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL509895 | BRUCEANTIN | — | 1 | 7.54 |
| CHEMBL250451 | BRUCEINE A | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL509895 | BRUCEANTIN | IC50 | = | 29.0 | nM | 7.54 |
| CHEMBL250451 | BRUCEINE A | IC50 | = | 1100.0 | nM | 5.96 |