Assay Detail
Functional
CHEMBL4712367
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human Panc-1 cells incubated for 72 hrs by sulphorhodamine B assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PANC-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.80 | 6.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL459546 | — | — | 1 | 6.44 |
| CHEMBL4759543 | — | — | 1 | 5.89 |
| CHEMBL4788345 | — | — | 1 | 5.06 |
| CHEMBL2029091 | — | — | 1 | - |
| CHEMBL2029092 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL459546 | — | IC50 | = | 360.0 | nM | 6.44 |
| CHEMBL4759543 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL4788345 | — | IC50 | = | 8700.0 | nM | 5.06 |
| CHEMBL2029091 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2029092 | — | IC50 | > | 100000.0 | nM | - |