Assay Detail
Functional
CHEMBL4712369
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Cytotoxicity against human MCF-7 cells incubated for 72 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.44 | 7.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL399894 | — | — | 1 | 7.20 |
| CHEMBL459546 | — | — | 1 | 7.08 |
| CHEMBL250451 | BRUCEINE A | — | 1 | 6.75 |
| CHEMBL4759543 | — | — | 1 | 4.72 |
| CHEMBL504960 | BRUCEOSIDE A | — | 1 | - |
| CHEMBL2029092 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL399894 | — | IC50 | = | 63.0 | nM | 7.20 |
| CHEMBL459546 | — | IC50 | = | 83.0 | nM | 7.08 |
| CHEMBL250451 | BRUCEINE A | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL4759543 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL504960 | BRUCEOSIDE A | IC50 | > | 50000.0 | nM | - |
| CHEMBL2029092 | — | IC50 | > | 50000.0 | nM | - |