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Assay Detail

CHEMBL4712385

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human A549 cells by SRB staining assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Autocuration

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones.
Ren Y,Kinghorn AD
J Med Chem (2020) 63 : 15410 -15448
PubMed 33289552 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.89 7.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4789549 1 7.77
CHEMBL4763211 1 7.12
CHEMBL4748991 1 5.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4789549 IC50 = 17.0 nM 7.77
CHEMBL4763211 IC50 = 75.0 nM 7.12
CHEMBL4748991 IC50 = 1700.0 nM 5.77