Assay Detail
Functional
CHEMBL4714889
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Antiproliferative activity against human A375 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A375/R |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-Activity Study of Nitazoxanide Derivatives as Novel STAT3 Pathway Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.03 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4746255 | — | — | 1 | 5.55 |
| CHEMBL1401 | NITAZOXANIDE | 4.0 | 1 | 4.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4746255 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL1401 | NITAZOXANIDE | IC50 | = | 31800.0 | nM | 4.50 |