Assay Detail
Functional
CHEMBL4715460
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Antiproliferative activity against human SUP-M2 cells assessed as cell growth inhibition incubated for 4 days by CellTiter-Glo asssay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SUPM2 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.31 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4776801 | — | — | 1 | 6.34 |
| CHEMBL4452527 | — | — | 1 | 6.28 |
| CHEMBL4575382 | — | — | 1 | - |
| CHEMBL4796524 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4776801 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL4452527 | — | IC50 | = | 530.0 | nM | 6.28 |
| CHEMBL4575382 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4796524 | — | IC50 | > | 10000.0 | nM | - |