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Assay Detail

CHEMBL4718374

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against human PBMC cells assessed as reduction in cell viability incubated for 72 hrs by Alamar blue assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type PBMC
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

7,7-Dimethylaporphine and Other Alkaloids from the Bark of Guatteria friesiana.
Costa EV,Pinheiro ML,Maia BH,Marques FA,Ruiz AL,Marchetti GM,Carvalho JE,Soares MB,Costa CO,Galvão AF,Lopes NP,Koolen HH,Bezerra DP,Barison A
J Nat Prod (2016) 79 : 1524 -1531
PubMed 27300257 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.46 4.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL37736 LIRIODENINE 1 4.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL37736 LIRIODENINE IC50 = 34800.0 nM 4.46