Assay Detail

CHEMBL4721906

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Modulator activity at rat PPARdelta

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Rattus norvegicus
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD).

Lagu B,Kluge AF,Tozzo E,Fredenburg R,Bell EL,Goddeeris MM,Dwyer P,Basinski A,Senaiar RS,Jaleel M,Tiwari NK,Panigrahi SK,Krishnamurthy NR,Takahashi T,Patane MA
ACS Med Chem Lett (2018) 9 : 935 -940
PubMed 30258544 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	8.00	8.00

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4649683	—	—	1	8.00

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4649683	—	EC50	=	10.0	nM	8.00