Assay Detail
Binding
CHEMBL4723091
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PI3K-delta (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (CHEMBL3130) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Research advances on selective phosphatidylinositol 3 kinase δ (PI3Kδ) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.72 | 8.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4760517 | — | — | 1 | 8.49 |
| CHEMBL4303323 | ACALISIB | 2.0 | 1 | 7.90 |
| CHEMBL4781969 | — | — | 1 | 6.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4760517 | — | IC50 | = | 3.2 | nM | 8.49 |
| CHEMBL4303323 | ACALISIB | IC50 | = | 12.7 | nM | 7.90 |
| CHEMBL4781969 | — | IC50 | = | 170.0 | nM | 6.77 |