Assay Detail
Binding
CHEMBL4723162
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of His-tagged SARS-CoV 3C-like protease (9970 to 10887 residues) expressed in African green monkey Vero cells assessed as reduction in cis-cleavage activity using SAVLQSGFRK as substrate by dual luciferase reporter assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Severe acute respiratory syndrome-related coronavirus |
| Cell Type | Vero |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.15 | 5.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1718454 | — | — | 1 | 5.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1718454 | — | IC50 | = | 7100.0 | nM | 5.15 |