Assay Detail
Binding
CHEMBL4723170
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SARS-CoV His-tagged papain-like protease expressed in Escherichia coli BL21 (DE3) CodonPlus-RIL cells using Arg-Leu-Arg-Gly-Gly-AMC as substrate by fluorescence method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Severe acute respiratory syndrome-related coronavirus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.43 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL457303 | BROUSSONOL E | — | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL457303 | BROUSSONOL E | IC50 | = | 3700.0 | nM | 5.43 |