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Assay Detail

CHEMBL4723456

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Functional
Antiproliferative activity against human Panel leukemia (Carcinoma cell lines) assessed as cell growth inhibition measured after 48 hrs by SRB assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Panel leukemia (Carcinoma cell lines)
Confidence 1 — Organism
Curated By Autocuration

Target

Panel leukemia (Carcinoma cell lines) (CHEMBL614083)
Type CELL-LINE
Organism Homo sapiens

Publication

N-phenyl ureidobenzenesulfonates, a novel class of promising human dihydroorotate dehydrogenase inhibitors.
Bouzriba C,Larcher L,Gagné-Boulet M,Fortin S
Bioorg Med Chem (2020) 28 : 115739 -115739
PubMed 33007554 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.09 6.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2165736 1 6.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2165736 IC50 = 810.0 nM 6.09