Assay Detail
Binding
CHEMBL4723495
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of N-terminus hexa-histidine tagged-SARS-coV guanine-N7 methyltransferase expressed in Escherichia coli using GpppAUAU RNA as substrate incubated for 30 mins by liquid scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Severe acute respiratory syndrome-related coronavirus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Druggable targets from coronaviruses for designing new antiviral drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.72 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL6246 | ELLAGIC ACID | 2.0 | 1 | 7.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL6246 | ELLAGIC ACID | IC50 | = | 19.0 | nM | 7.72 |