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Assay Detail

CHEMBL4723666

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MDA-MB-468 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-468
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-468 (CHEMBL614335)
Type CELL-LINE
Organism Homo sapiens

Publication

Design, synthesis and biological evaluation of new bivalent quinazoline analogues as IAP antagonists.
Bae I,Kim D,Choi J,Kim J,Kim M,Park B,Kim YH,Ahn YG,Hyung Kim H,Kim DK
Bioorg Med Chem Lett (2021) 34 : 127676 -127676
PubMed 33166687 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.56 7.56

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4753756 1 7.56

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4753756 IC50 = 27.8 nM 7.56