Assay Detail
Functional
CHEMBL4723722
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human KMM-1 cells after 48 hrs by PrestoBlue cell viability assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KMM-1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antimyeloma Potential of Caffeic Acid Phenethyl Ester and Its Analogues through Sp1 Mediated Downregulation of IKZF1-IRF4-MYC Axis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.06 | 5.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4569185 | — | — | 1 | 5.72 |
| CHEMBL4758744 | — | — | 1 | 5.18 |
| CHEMBL131982 | — | — | 1 | 4.92 |
| CHEMBL319244 | CAFFEIC ACID PHENETHYL ESTER | — | 1 | 4.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4569185 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL4758744 | — | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL131982 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL319244 | CAFFEIC ACID PHENETHYL ESTER | IC50 | = | 37500.0 | nM | 4.43 |