Assay Detail
Functional
CHEMBL4723724
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human MM1.R cells after 48 hrs by PrestoBlue cell viability assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MM.1R |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antimyeloma Potential of Caffeic Acid Phenethyl Ester and Its Analogues through Sp1 Mediated Downregulation of IKZF1-IRF4-MYC Axis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.50 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4569185 | — | — | 1 | 6.22 |
| CHEMBL4758744 | — | — | 1 | 5.70 |
| CHEMBL131982 | — | — | 1 | 5.31 |
| CHEMBL319244 | CAFFEIC ACID PHENETHYL ESTER | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4569185 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4758744 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL131982 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL319244 | CAFFEIC ACID PHENETHYL ESTER | IC50 | = | 17800.0 | nM | 4.75 |