Assay Detail
Binding
CHEMBL4723751
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Binding affinity to STK17A (unknown origin) by KINOMEscan scanMAX assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 6.21 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1836719 | — | — | 1 | 6.64 |
| CHEMBL1836641 | — | — | 1 | 6.60 |
| CHEMBL1836721 | — | — | 1 | 6.57 |
| CHEMBL4763392 | — | — | 1 | 5.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1836719 | — | Kd | = | 230.0 | nM | 6.64 |
| CHEMBL1836641 | — | Kd | = | 250.0 | nM | 6.60 |
| CHEMBL1836721 | — | Kd | = | 270.0 | nM | 6.57 |
| CHEMBL4763392 | — | Kd | = | 9800.0 | nM | 5.01 |